I can only have a distraction going if the work I'm doing is something tedious, like animating. During one animation project, back when I had my second monitor working, I watched all 5 seasons of Daria while rotoscoping. These days I listen to Radiolab, TIGRadio, the IndieGames.com podcast, and the Infinite Ammo podcast. I've exhausted almost all of them and I'm looking for something new; might have to finally get into Fresh Air or This American Life, but it's daunting having years and years of content to sift through.
If I'm making something like character art or backgrounds, I can't listen to anything with words. I dunno, I need my language centers completely focused on what I'm doing. But sometimes I can handle listening to instrumentals; for that, I like Headphone Science