So as a video guy who loves working with Adobe After Effects, I've done a few projects with 2D pixelated sprites in 3D spaces.
My first significant attempt was a 3D recreation of the Winters area from Earthbound
, which I did for starmen.net's 2011 Earthbound Fanfest (I also did the instrumental cover behind it). Got first in Audio/Vis!
Since then, I did an intro for twitch.tv webcaster MANvsGAME (who's awesome!) in the same sort of style, except this time I, did the pixel art myself: MANvsGAME Intro
edit: I should add that MAN is friends with Souleye of VVVVVV fame, who did the intro music! Kickass.
I have a lot of fun doing these, but I don't know what they're good for besides fan stuff and in support of video content. Trailers? But then the trailer isn't representative of the gameplay. Thoughts appreciated.