I just registered to this forum because of BlockScape.
I think it has a lot of potential because of the much smaller block sizes where you can build much more precise.
At the moment I'm using the demo version. It seems my game crashes when there is a lot new render information, i.e. running through a cave very fast. If it helps I could post or PM the error message.
Yes please!
My system consists of a Core i7 2600K with 16 GB RAM and a Geforce 570 GTX with 1280 MB, and the OS is Win 7 Ultimate x64.I think the hardware shouldn't be the problem.
When I bought the machine I'm using to develop Blockscape none of the hardware or software you mention existed.

What I am missing at the moment:
1. A little more information / tooltips! I have a lot of stuff in the inventory and don't know what it is. OK, I can identify sand, water, wood or stone, but when I dig around in caves I get several items which I can't really identify.
On my todo list now.
2. Night / Day change - will this come in the future?
Yes, in the near future.
3. Multiplayer - as far as I know it is in developement
Yes, within a week if all goes well.
4. The shadows are nice, but the world looks too dark and unfamiliar with it.
When the direct lighting is perfect (there are a few minor issues) I will enable secondary reflections which will brighten up some of the shadows.
5. Keyboard layout should be editable
On my todo list.
6. What about crafting? Is it planned?
The game uses something I call autocrafting: Crafted items/materials becomes available as soon as you mine the required base materials. I will probably make this optional in the future.
7. Will there be any AI Mobs / NPCs?
Yes! A concept artist and I are working to breathe life into Blockscape for phase 2.
On the website there is way too less info about this game. I hope there will be more information soon, because it is really nice and has potential.
I will try to update it with more information in next couple of days.
thank you for the feedback!
Jens