I guess the question is, how badly you want to make a sustainable living for yourself as an indie game dev. To me it's looks pretty similar to any other kind of start-up business. You've got to be willing to work for pretty much no pay for an uncertain period before you get a return on investment.
I guess if you value ambition, autonomy, not playing by the rules more than security and consistency then going full-time would be your thing. If it's the opposite that makes you happy then stick to that, and I guess that's the key factor: what is making you happy.
For me personally, I'm probably in a similar position to Gregg above when he started out. I've got a ton of financial obligations, family, etc and walked away from a very high paying position in IT, and have eventually ended up doing indie game dev which has been my dream since I've been 4. On the financial side, I earn about as much as when I was a grad about a decade ago, but on the other hand I finally feel like I have some job satisfaction
So yeah, look at what makes you truly happy.