Great game, overall. I've been playing it all saturday, and mostly loving it.

Couple issues:
1:

The shopkeep was guarding the exit. I was trying to work my way around him, to blow him up and get the damsel through the door, but I ran out of time and the ghost appeared, so I dodged past him and into the door. I actually made it into the exit door, and was playing the "walk into backround" animation, when the shopkeep jumped up and shotgunned my disappearing form. I rocketed dead out of the door and got gameover. Total bullshit.
I've walked through the statue spikes in the jungle areas through the exit doors but the damn shopkeeper can pull me back from having BEAT the level to kill me. Please make the PC totally invulnerable while playing the leaving animation. Pretty please.

2: Please add "no music" to the pre-launch options (where you pick fullscreen and can configure controls etc). I know you can mute the music with M, but only because of this thread. The music's nice, but wears after a while.
3. I ran into a bug with a boulder.

It rolled for about 3 seconds then came to a sudden complete stop at that point. No idea why. It broke about 4-5 tiles before freezing.
4. The pathing for the jungle stages frequently ends up with dead ends that are impossible to get around without bombs, especially when the spike statues are involved.

I know you want the game to get harder as it goes along but the frogs and venus spelunker traps and permadeath alone do that just fine. It's an issue of fairness, and I'd personally prefer that the game always has a path from start to finish that you can follow without specifically using up a bomb or rope, though it may be difficult. In general the statues and trees seem to be completely ignored for when the game checks a level to see if it's got a completable path. Overall the level generation program is very, very impressive with this game, and for the starting areas it makes it feel that every level is hand-made and deliberately laid out and paced, which makes these moments seem just that much worse in comparison.
Edit: The top scores thing is a bit off. This is right after the game over in the first pic:

The money score is off by a couple thousand.
Edit 2:

I jumped on this giant spider from above and passed right through it and its web without stopping or hitting it and dropped to the floor below (I took a point of damage from the fall).