This topic has been pretty interesting, actually. I posted this on, of all places, a Cincinnati Bengals' forum I visit and got some very different, though surprisingly valid, opinions.
Of all the info and opinions I've gathered, it seems the end result is that the style is fine and works well for the game, but small tweaks should be applied to her face in order for it to work. She's not as pretty as she could be, but switching to anime or 90's Disney doesn't need to be the answer.
Thanks again for your takes on this, everyone. I'm going to -carefully- broach the subject with the artist and see what he thinks. If all goes well, I'll have an update for you in a few days, hopefully.
Oh, and as for using over the top anime expressions with western/hybrid styles... I absolutely HATE that. Despite how good Avatar and Teen Titans are supposed to be, I just can't force myself to watch it because of the abuse of crazy anime expressions. Things like that definitely won't end up in this game.
I'm not a great artist myself, but I tried modifying the face as per some of the suggestions. Nothing major, but I actually think these few changes make a big difference. I moved her eyes and eyebrows down a bit, tilted her nose up a bit and shortened her neck. It turned out a lot better than I expected...