Thanks, guys!
Would the small icons still be used for other purposes?
Yeah, the bigger icons are not meant to substitute the smaller ones.
I was thinking something a bit like this. I still need to work on adding more space to it and a bit more flourish. I think working on the UI is really tedious, so this is where I usually get stuck and end up working on something else.
I've been thinking some more about the wolves, and I found an old doodle of mine which is a little closer to what I want.
This is the regular wolf portrait. I'm going to draw a new portrait for the altered wolf, but for now I decided to experiment a little.
I might have to make some more drastic changes to it, like how the skull is deformed in the drawing. The altered wolf sprite will be a little bigger than the regular wolf, but I want it to be clear that they're different creatures. Relying on facial features to show the difference might be insufficient.
This is the regular wolf sprite so far, and it doesn't really suit subleties. I'll add a bit more contrast to it later.