Hi, I don't have any personal experience to apply here, but have you ever come into contact with
2xSai or EAGLE? (Wikipedia lists a couple other scaling algorithms designed specifically for use with pixel art also). Some emulators I have used use these and they are the only kind of scaling I as a player am able to put up in emulators. It seems like pixel art invariably winds up incorporating sharp edges, and so then if you scale in any traditional manner it makes these edges look muddy. (Of course I imagine if you
designed the art to look good with some kind of trilinear/asintropic scaling then it would indeed look good?)
Anyway the neat thing about the 2xSai/eagle algorithms in specific is that since they seem to sort of straighten out lines and smooth areas of color:
...they actually sort of look better the more heavily you apply them, if you apply 2xSai on top of 2xSai on top of 2xSai you wind up with this
really interesting stylized look that makes everything look like everything's been drawn with a sharpie and a straightedge.